Medicine before surgery to reduce pain
Part of Brain & nervous system clinical trials.
This study tests whether giving a medicine called dexmedetomidine before surgery can reduce pain during and after the operation. If it works, it might help people wake up feeling better and need less pain medicine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old.
- Your weight is within a healthy range for your height (BMI 18.5–35).
- You are in good enough health for surgery (ASA grade I–III).
- You are having non-heart surgery with general anesthesia (being fully asleep).
- Your operation is expected to last between 30 minutes and 3 hours.
- You do not have serious brain, heart, liver, kidney, or lung problems, and you have not had brain surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether dexmedetomidine can reduce pain after elective shoulder arthroscopy surgery done under general anesthesia. If you’re eligible, it may help improve postoperative comfort and reduce the need for additional pain treatment.
This study tests a combination of two medicines given through an IV after spine surgery to see if it controls moderate to severe pain better. It may help reduce pain and improve recovery.
This trial tests if giving two medicines, dexmedetomidine and esketamine, during and after surgery can help you feel better and recover more comfortably. It is for adults having general anesthesia for at least one hour who will use a patient-controlled pain pump afterward.
This trial tests whether a nasal spray with a calming medicine (dexmedetomidine) can reduce anxiety before brain surgery. It is given before the operation to help you feel more relaxed and calm.
This study tests whether combining two medicines, dexmedetomidine and esketamine, during spine surgery can help prevent chronic pain that sometimes continues for months after surgery. If you are having spine surgery and will use a pain pump afterward, this trial might be a good fit for you.
This study tests whether a combination of two medicines, dexmedetomidine and esketamine, can help improve sleep problems after major non-heart surgery. You may be eligible if you are having planned surgery lasting at least one hour and will use a pain pump after surgery.
Hear when a new Pain Management trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.