Nanocrystalline megestrol acetate for liver cancer wasting
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a drug called nanocrystalline megestrol acetate to help people with advanced liver cancer who are losing weight and muscle mass. It's for those who have not yet had systemic therapy and are receiving other cancer treatments at the same time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have hepatocellular carcinoma (liver cancer) that cannot be completely removed by surgery.
- Your cancer is at an advanced stage (BCLC stage B or C) and you have not had systemic therapy before.
- Your liver function is good enough (Child-Pugh class A or B7).
- You have at least one tumor that can be measured on a scan.
- You have pre-cachexia or cachexia (weight loss, muscle loss, or loss of appetite) as defined by the Fearon criteria.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a medication called megestrol acetate can help improve appetite and prevent weight loss in patients with advanced liver cancer who are receiving combination cancer treatment. The study compares the medication to placebo (inactive pill) to see if it helps patients feel hungrier and maintain their weight during treatment.
This trial tests a newer form of megestrol acetate (a medication that can help with appetite and weight) given alongside standard chemotherapy and radiation for locally advanced cervical cancer that cannot be removed by surgery. The study aims to see if this combination is safe and effective.
This study tests a special form of megestrol acetate (a medicine that can help with appetite and weight gain) in people with advanced digestive system cancers who are about to start or are already taking a type of targeted therapy called a TKI. The goal is to see if it helps with cancer-related weight loss and wasting (cachexia).
This trial tests a new appetite-boosting medicine (nano-crystalline megestrol acetate) added to standard chemotherapy for people with advanced small cell lung cancer who are losing weight. It aims to see if it helps with weight, strength, and treatment response.
This study tests a special form of the drug megestrol acetate (Megace) in cancer patients who have lost weight and appetite (cachexia). It aims to see if this medication can help improve weight gain and quality of life.
This trial tests a medicine called nanocrystalline megestrol acetate to help people with advanced small cell lung cancer who have lost weight and appetite. The goal is to see if the drug can improve their condition.
Hear when a new Cachexia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.