Comparing two treatments for H. pylori infection
Part of Digestive system, Infections clinical trials.
This trial tests two different ways to treat Helicobacter pylori (H. pylori), a bacteria that can cause stomach ulcers. One treatment combines three medicines (bismuth, amoxicillin, and vonoprazan), and the other uses four medicines (bismuth quadruple therapy). The goal is to see which works better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have an H. pylori infection.
- You are not allergic to any of the study medicines.
- You have not had stomach surgery.
- You do not have severe liver or kidney disease.
- You have not had cancer in the last five years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests two different combinations of medications to treat H. pylori, a stomach bacteria that can cause ulcers. You would take one of the two combinations for a short time to see which works better at getting rid of the infection.
This study compares two different antibiotic combinations (metronidazole vs. tinidazole, both with bismuth and other medicines) to see which works better at getting rid of H. pylori, a bacteria that can cause stomach ulcers. If you have H. pylori and haven't been treated before, you may be able to help us find the best option.
This trial compares two different antibiotic combinations to treat H. pylori, a common stomach bacteria that causes indigestion and ulcers. One uses a newer acid-blocking medicine (vonoprazan) and the other uses a standard one (esomeprazole), both paired with antibiotics.
This trial compares a newer drug (vonoprazan) plus antibiotics to the standard triple therapy for eradicating H. pylori infection in the stomach. It may be a good option if you have stomach symptoms like indigestion, acid reflux, or a non-bleeding ulcer and have not been treated for H. pylori before.
This trial tests if a newer acid-blocking medicine works better than a standard one when given with antibiotics and bismuth for treating H. pylori infection, a bacteria that can cause stomach ulcers. It is for adults who have not had treatment for H. pylori before.
This trial tests a new two-step antibiotic treatment for adults with chronic gastritis caused by H. pylori bacteria. If you have not been treated for H. pylori before and are between 18 and 70, you may be able to join.
Hear when a new Helicobacter Pylori Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.