Can a blood test replace invasive screening in Lynch syndrome?
Part of Cancer, Digestive system, Genetic & congenital, Hormones & metabolism clinical trials.
This study tests whether a simple blood test (called a liquid biopsy) can safely replace some invasive cancer screening procedures for people with Lynch syndrome. It aims to find cancer early with less discomfort.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 35 and 80 years old.
- You have Lynch syndrome, confirmed by a genetic test showing a change in one of the genes MLH1, MSH2, MSH6, or EPCAM.
- You have not had surgery to remove your entire colon and rectum.
- You have not had active cancer treatment in the last 2 years (except some types of immunotherapy).
- You have not taken a specific type of immunotherapy called a checkpoint inhibitor in the last 12 months.
- You have health insurance or are covered by a national health system for your routine cancer checks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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