New drug plus standard maintenance for recurrent ovarian cancer
Treatments studied
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This trial tests a new experimental drug (JPI-547) combined with bevacizumab (a targeted therapy) as maintenance treatment for recurrent ovarian cancer after initial response to platinum-based chemo. The goal is to see if this combination can keep the cancer from growing longer than standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have recurrent ovarian, fallopian tube, or primary peritoneal cancer that is a high-grade serous or grade 2/3 endometrioid type.
- You have received platinum-based chemotherapy and then a PARP inhibitor as maintenance therapy.
- Your cancer responded to the platinum-based chemotherapy you had before joining this trial.
- You are physically well enough to be fully active or only limited in strenuous activity (ECOG 0 or 1).
- You have adequate blood, kidney, and liver function, and are willing to use contraception if you could become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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