Study of PF-08634404 plus chemo for stomach and esophagus cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a new study drug called PF-08634404 in combination with standard chemotherapy for people with stomach, gastroesophageal junction, or esophagus cancer that has spread. It aims to see if adding this drug helps the treatment work better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with adenocarcinoma in the stomach, gastroesophageal junction, or esophagus.
- Your cancer is locally advanced or has spread to other parts of the body (metastatic).
- You are able to perform daily activities with little or no help (ECOG 0-1).
- You have not received any systemic treatment (like chemotherapy) for your advanced or metastatic disease.
- Your tumor is HER2-negative and PD-L1 positive based on local lab tests.
- Your liver and kidneys are functioning well enough.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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