Do family voices affect brain chemistry and pain in ICU patients?
Treatments studied
Part of Pain clinical trials.
This study tests whether hearing a family member's voice can change natural brain chemicals (dopamine and serotonin) and reduce pain for people in the intensive care unit who are in a coma but can still react. It may help improve comfort during recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You are currently in the intensive care unit (ICU).
- You have not had anything to eat or drink in the last hour.
- You are in a deep coma but able to react (GCS 3–8 and RASS -3 to +2).
- You have no hearing problems or recent ear surgery.
- You have not taken cortisol, serotonin, or dopamine hormones in the last 48 hours.
- You have not taken pain medicine in the last 4 hours.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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