Balloon with or without plaque removal for blocked leg arteries
Part of Heart & circulation clinical trials.
This study compares two ways to open a completely blocked artery in the leg: using a paclitaxel-coated balloon alone, or first removing some blockage with a special device (debulking) before using the balloon. It aims to see which approach gives better long-term results for people with chronic leg artery blockages.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old
- You have leg pain or skin ulcers due to poor blood flow in your legs (called Rutherford category 2–5)
- You have a blocked or narrowed artery in your thigh or behind the knee that can be treated with a balloon
- Your doctor has been able to pass a thin wire through the blockage (guidewire test)
- You are not having a sudden clot that needs emergency treatment, and you do not have a bleeding disorder or serious kidney disease
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares a special drug-coated balloon/stent strategy versus a standard stent approach for people with blocked thigh artery segments. It aims to improve how long the artery stays open and reduces repeat procedures.
This trial tests a drug-coated balloon to open blocked or narrowed arteries in the thigh or behind the knee. The drug may help keep the artery open longer.
This trial is testing a special balloon coated with the drug paclitaxel to open up long blockages in the leg artery (femoropopliteal). The goal is to see if it is safe and effective for improving blood flow and symptoms like pain or ulcers.
This trial tests a special balloon coated with a drug (paclitaxel) to open blocked leg arteries, aiming to improve blood flow and reduce symptoms like leg pain when walking. It is for people with moderate to severe leg artery disease who have not had prior stents or bypass in the treated area.
This trial is testing a special balloon coated with a drug (paclitaxel) to treat narrowed or blocked arteries in the leg. It aims to see how well this balloon works to keep the artery open.
This study compares two ways to open a blocked artery in the leg: using a special balloon that releases medicine to prevent re-blockage, versus placing a small metal tube (stent) coated with medicine. The goal is to see which approach better keeps the artery open and relieves leg symptoms.
Hear when a new Femoropopliteal Artery Occlusion trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.