Lidocaine and ketamine for severe cancer pain not helped by opioids
Part of Cancer, Mental health, Pain clinical trials.
This trial tests if adding lidocaine and ketamine to your current pain medicines can better control severe cancer-related pain that opioids alone haven't helped.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have chronic cancer-related pain that is moderate to severe (at least 4 on a 0–10 pain scale)
- You are already taking strong opioid pain medicine (at least 60 mg of morphine per day or the most you can tolerate)
- If your pain has a nerve-related (neuropathic) component, you have tried at least one nerve pain medicine (like amitriptyline, duloxetine, gabapentin, pregabalin, or venlafaxine)
- You do not have serious liver, kidney, heart, or thyroid problems, porphyria, or a history of psychosis, schizophrenia, or substance abuse
- You are not pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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