Amniotic membrane to prevent mesh exposure after vaginal surgery
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests if placing a human amniotic membrane over surgical mesh during vaginal repair for pelvic organ prolapse can reduce the risk of the mesh pushing through the vaginal tissue. The study is for women who have not had a hysterectomy and may also have stress urinary incontinence.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have pelvic organ prolapse stage II or greater, with the lowest part of the prolapse at least 1 cm past the hymen.
- You have not had a hysterectomy.
- You may also have stress urinary incontinence (leaking urine when you cough, sneeze, or exercise).
- You have not had previous vaginal or abdominal surgery using synthetic mesh for prolapse repair.
- You are willing to come back for follow-up visits for at least 12 months after surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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