Clin2
NCT07419854Possibly a fitRecruiting

Restoring facial fullness after GLP-1 weight loss with Radiesse

Volume Loss (Soft Tissue Ptosis or Atrophy )

Part of Skin clinical trials.

This trial tests whether a facial filler called Radiesse can restore volume lost during weight loss from GLP-1 medications (like Wegovy or Mounjaro). It's for adults just starting GLP-1 therapy who expect to lose 20 pounds or more and want to see if fillers can help their face look fuller.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
48 people
Ages
21 years to 65 years
Study type
Interventional

Who can take part

  • You are between 21 and 65 years old.
  • You are just starting a GLP-1 medication (like semaglutide or tirzepatide) for weight loss or diabetes weight management and plan to lose at least 20 pounds.
  • Your body mass index (BMI) is between 24 and 32.
  • You have enough facial fat (your face is not already very hollow) and are willing to get facial filler injections.
  • You have not had any facial cosmetic procedures in the last 2 years (like fillers, fat transfer, or lifts) or certain treatments in the last year or 4 months.
  • You do not have severe acne, psoriasis, or scars on your face, and you are not allergic to calcium hydroxylapatite (Radiesse) or lidocaine.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07221461Not yet recruiting· Phase 2
Skin filler for skin quality in women on GLP-1 medications

This study tests whether a hyaluronic acid filler (a common wrinkle-smoothing treatment) can improve skin quality in women who are taking GLP-1 medications for weight or diabetes. It aims to see if the filler can help with common skin changes like loss of firmness and wrinkles.

San Diego, California
NCT07558603Not yet recruiting
Skin serum for menopausal women on weight-loss meds

This study tests a skin serum to improve facial aging signs like fine lines and dullness. It is for post-menopausal women aged 45-65 who are taking a GLP-1 medication (e.g., Ozempic, Wegovy).

San Diego, California
NCT07216352Not yet recruiting
Topical serum for facial aging in people taking GLP-1 medications

This study tests a topical serum to improve visible signs of facial aging in people who are currently taking a GLP-1 medication. If you qualify, you'll use the serum for the study period and see if it helps with fine lines, sagging, and skin texture.

San Diego, California
NCT07478198Enrolling by invitation
PLLA injections for facial sagging after weight loss drug use

This trial tests whether PLLA injections can safely improve facial sagging in people who lost weight on GLP-1 drugs. If you are between 30 and 60, have noticeable sagging or smile lines, and have not had other facial treatments recently, this may be an option.

Shanghai, Shanghai Municipality
NCT07202117Recruiting· Phase 4
Injectable fillers for cheek and chest rejuvenation

This study tests two types of injectable fillers, PLLA and CaHA-R, to improve skin texture and tightness in the cheeks and chest area. It may be a good option for women looking to treat mild to severe skin irregularities.

Montreal, Quebec
NCT05522426Not yet recruiting
Facial fat grafting with new fat processing device

This study tests a new device that processes your own fat (taken from your body) to use for facial fat grafting, which may help improve facial contours or volume. It is for people who are interested in using their own fat for facial rejuvenation and are willing to avoid other facial cosmetic procedures during the study.

Newport, California

Hear when a new Volume Loss (Soft Tissue Ptosis or Atrophy ) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.