How dexamethasone affects drug processing in healthy men
Treatments studied
This study tests how a common steroid medicine called dexamethasone affects the way your body processes other drugs. Healthy men will take the medicine and have blood tests to see how their liver enzymes work.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be a healthy man aged 19 to 50 years
- Weigh between 50 kg (about 110 lbs) and 90 kg (about 198 lbs), with a body mass index between 18.5 and 29.9
- Have a specific genetic type (CYP2C19) that is either normal or poor metabolizer—this will be checked by a blood test
- Have no significant medical conditions, and not be taking certain medications, supplements, or herbal products
- Be a non-smoker (or quit at least 3 months ago) and avoid alcohol, caffeine, and grapefruit during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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