Numbing medicine for pain after appendix removal
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests whether numbing medicine (bupivacaine) placed into the belly during an open appendix removal helps reduce pain after surgery, compared to a placebo (a shot with no medicine).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having an open appendectomy (surgery to remove your appendix through a cut in your belly).
- Your appendix has not burst (perforated) and you do not have an abscess or fluid collection around it.
- You do not have uncontrolled diabetes or high blood pressure.
- You do not have a long-term kidney or liver disease, an active stomach ulcer, or a psychiatric condition.
- You are not pregnant and are not allergic to the medicines bupivacaine or ketorolac.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if adding dexmedetomidine to bupivacaine (a numbing medicine given near the tailbone) provides better pain relief during and after appendix surgery in children. It may help reduce the need for other pain medicines.
This study compares two different injection techniques to reduce pain after appendix removal surgery in children ages 7–12. Both techniques use ultrasound (sound waves) to guide a numbing medication to nerves near the surgical area, and researchers want to see which works better.
This trial compares two medications added to a numbing injection around your abdominal muscles during belly surgery to help manage pain after surgery. The study aims to find which combination works better and lasts longer.
This study compares two ways of numbing the belly during laparoscopic appendix removal in children. It aims to find which method gives better pain relief after surgery.
This study tests whether injecting a numbing medicine at the surgery site reduces pain after laparoscopic abdominal surgery. It may help patients have less pain and recover more comfortably.
This trial compares two types of nerve blocks (M-TAPA and TAP) to see which provides better pain relief after laparoscopic appendix removal. If you are having this surgery, you may experience less pain and need fewer painkillers.
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