Clin2
NCT07431502Possibly a fitNot yet recruiting

HPV vaccine to prevent recurrence of pre-cancerous lesions

Patients With Primary HPV High-grade Squamous Intra-epithelial Lesions (HSIL) at Vulvar SitePatients With Primary HPV High-grade Squamous Intra-epithelial Lesions (HSIL) at Vaginal SitePatients With Primary HPV High-grade Squamous Intra-epithelial Lesions (HSIL) at Penile SitePatients With Primary HPV High-grade Squamous Intra-epithelial Lesions (HSIL) at Cervical SitePatients With Primary HPV High-grade Squamous Intra-epithelial Lesions (HSIL) at Anal Site

Treatments studied

Part of Cancer, Immune system & allergy, Infections, Women’s health & pregnancy clinical trials.

This trial tests whether a vaccine against HPV can help prevent pre-cancerous lesions from coming back after you've had them. It's for people who have had high-grade pre-cancerous lesions but haven't yet been treated for them.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
984 people
Ages
18 years to 55 years
Study type
Interventional

Who can take part

  • You are between 18 and 55 years old.
  • You have a biopsy-confirmed high-grade pre-cancerous lesion (HSIL) in the genital or anal area.
  • You have not been treated for HSIL before.
  • You have never received an HPV vaccine.
  • You have not had HPV-related cancer (such as cervical or anal cancer).
  • If you have HIV, your viral load must be undetectable while on anti-HIV medication.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06052696Recruiting· Phase 4
HPV vaccine after treatment for vulvar high-grade lesions

This trial tests whether getting the HPV vaccine after treatment for vulvar high-grade lesions can help prevent the lesions from coming back. It is for women who have not been vaccinated before and are about to have treatment for this condition.

Rotterdam
NCT07077980Not yet recruiting
HPV vaccine for cervical cancer

This trial aims to develop a vaccine that trains your immune system to fight HPV, the virus that causes cervical cancer. By studying your blood, researchers hope to find better ways to prevent the cancer from coming back.

Hefei, Anhui
NCT06210854Recruiting· Phase 2
HPV16/18 Vaccine Trial for Cervical Lesions

This trial tests a new vaccine (pBI-11) given with a device that uses mild electric pulses to help the vaccine enter cells. It is for people who have HPV16 or 18 but no high-grade cervical changes.

Birmingham, Alabama
NCT06658405Recruiting· Phase 2
HPV vaccine after cervical lesion treatment

This trial tests whether an HPV vaccine (Gardasil 9) can help women over 45 who still have HPV after treatment for a high-grade cervical lesion. It compares vaccinated and unvaccinated patients to see if vaccination lowers the risk of the lesion coming back.

Lille
NCT05334706Recruiting· Phase 4
Vaccine study to lower HPV spread in HPV-positive women

This Phase 4 study tests whether a 9-type HPV vaccine (9vHPV) can reduce how infectious HPV is and lower the chance of HPV spreading in women who already have HPV16 and/or HPV18. It focuses on specific HPV-positive women recently diagnosed and compares what happens after vaccination.

L'Hospitalet de Llobregat, Catalonia
NCT03848039Not yet recruiting· Phase 3
HPV vaccine after LEEP to prevent cervical changes from returning

This trial tests whether getting the HPV vaccine after a LEEP (a procedure to remove abnormal cervical cells) can help prevent the abnormal cells from coming back. It's for women who have had high-grade cervical changes or very early cervical cancer.

Hear when a new Patients With Primary HPV High-grade Squamous Intra-epithelial Lesions (HSIL) at Vulvar Site trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.