Spinal stimulation and drug therapy for motor skills in cerebral palsy
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests if combining spinal cord stimulation with a drug called 5-azacitidine can improve movement and muscle control in children with cerebral palsy. It aims to help with daily activities like walking or using hands.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Diagnosed with cerebral palsy (spastic type affecting one side, both legs, or all limbs) and classified as any level from I to V on the Gross Motor Function Scale (a measure of movement ability).
- Age between 4 and 17 years old.
- Able to follow simple instructions and communicate yes or no clearly.
- No other major health issues, like uncontrolled seizures, serious heart or lung problems, or recent surgeries.
- No implanted medical devices like a pacemaker or drug pump.
- Not pregnant and not planning vaccines within 30 days of the study treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a smart ankle brace combined with a medicine called 5-azacitidine can improve walking ability in children with cerebral palsy. The study compares the medicine to a placebo to see if it helps enhance mobility.
This study tests whether a mild electrical stimulation applied to the skin over the spine can help children with cerebral palsy improve their movement and walking. Researchers will compare children who receive this treatment with children who don't have cerebral palsy to see if it makes a real difference.
This study tests whether combining brain stimulation with physical therapy can improve movement and muscle control in children with spastic cerebral palsy. Researchers will measure how the brain responds to this combined treatment.
This study tests whether repetitive transcranial magnetic stimulation (rTMS)—a non-invasive brain stimulation technique—can improve movement and function in children and teens with cerebral palsy. Researchers will also measure brain activity changes using EEG to understand how the treatment works.
This study tests whether a gentle electrical stimulation on the skin can improve movement and daily function in adults with cerebral palsy who have limited mobility.
This study tests spinal stimulation and mobility-related devices to see if they can improve how well you move. You would visit a lab, do simple movement tasks, and share feedback about comfort and what you experience.
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