Clin2
NCT07444541Possibly a fitRecruiting

Study of ANO31905 plus chemo for CLDN18.2-positive pancreatic cancer

Pancreatic Cancer

Treatments studied

Part of Cancer, Digestive system, Hormones & metabolism clinical trials.

This trial tests a new drug called ANO31905 added to standard chemotherapy for people with advanced pancreatic cancer that has a specific protein called CLDN18.2 on its cells. The study aims to see if the combination works better than chemo alone.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
84 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older
  • You have advanced pancreatic cancer that cannot be removed by surgery or has spread to other parts of the body
  • Your tumor must test positive for a protein called CLDN18.2
  • You have not received any previous cancer treatment for your pancreatic cancer
  • You are in relatively good health (able to do daily activities without much help)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05827796Recruiting· Phase 1/Phase 2
Testing IN10018 plus chemo with an added antibody in pancreatic cancer

This Phase 1/2 trial tests a new medicine (IN10018) and a specific added antibody (KN046) together with standard chemotherapy for advanced pancreatic cancer. It aims to see whether this combination can better control the cancer and how safely it can be given.

Shanghai, Shanghai Municipality
NCT07108504Not yet recruiting· Phase 2
Targeted therapy combined with chemotherapy for advanced pancreatic cancer

This trial tests a new targeted drug (LM-302) combined with a standard chemotherapy drug (gemcitabine) for people with advanced pancreatic cancer that has progressed after initial treatment. The goal is to see if this combination can slow down or shrink the cancer.

NCT07079228Recruiting· Phase 3
Comparing a new drug with chemo for pancreatic cancer

This trial tests a new treatment called QLS31905 plus chemotherapy against a placebo plus chemotherapy for people with advanced pancreatic cancer that hasn't been treated yet. It aims to see if the new combination works better.

Beijing
NCT07383922Not yet recruiting· Phase 3
FG-M108 plus chemotherapy for pancreatic cancer

This trial tests a new medicine (FG-M108) combined with chemotherapy for pancreatic cancer that is advanced or has spread. The medicine targets a protein found on some pancreatic cancer cells, and the goal is to see if it helps shrink tumors or slow the cancer more than chemotherapy alone.

Shanghai
NCT06953999Recruiting· Phase 3
Testing immunotherapy plus chemo for metastatic pancreatic cancer

This trial tests a new immunotherapy drug called ivonescimab combined with chemotherapy, with or without another experimental drug (AK117), for people with pancreatic cancer that has spread. The goal is to see if adding these therapies can help shrink tumors or slow the cancer's growth.

Harbin, Heilongjiang
NCT05035147Recruiting· Phase 4
Albumin-bound paclitaxel plus gemcitabine for advanced pancreatic cancer

This trial studies a chemotherapy combination (albumin-bound paclitaxel and gemcitabine) as first treatment for pancreatic cancer that cannot be removed by surgery. It aims to improve outcomes by testing how well this treatment works in people with locally advanced or metastatic disease.

Tianjin, Tianjin Municipality

Hear when a new Pancreatic cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.