Clin2
NCT07448753Possibly a fitEnrolling by invitation

Testing for genetic causes of chronic intestinal blockage

Pseudo Obstruction

Part of Digestive system clinical trials.

This trial checks if a genetic test can find causes of a rare condition where the intestines don't move normally, causing blockages. It may help people with poor esophagus muscle function.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
20 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 years or older.
  • You have chronic intestinal pseudo-obstruction, meaning your intestines act blocked without a physical blockage.
  • Your esophagus shows weak or no squeezing during a special swallow test (high-resolution manometry).
  • Your condition is not caused by another disease like an autoimmune disorder (checked by blood tests).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05132816Recruiting
Test manometry after partial anti-reflux surgery

This study checks how well a swallowing test called high-resolution manometry works after partial anti-reflux surgery. It focuses on adults with certain abnormal esophagus muscle patterns to help doctors understand what to expect after the operation.

Schlieren, Canton of Zurich
NCT06943417Not yet recruiting
Testing a deeper intestinal biopsy for chronic intestinal pseudo-obstruction

This study tests a new way to take a deeper tissue sample (biopsy) from the intestine during an endoscopy to better understand chronic intestinal pseudo-obstruction. The goal is to find out if it's safe and helpful for people like you.

Narita
NCT06687564Recruiting
Study of ACTG2 gene changes in children with intestinal blockage

This study looks at how changes (mutations) in a gene called ACTG2 affect the muscles that move food through the gut in children and adults with a rare condition called pediatric intestinal pseudo-obstruction (PIPO). It may help researchers understand the condition better and find new ways to help patients.

Montpellier
NCT06567691Enrolling by invitation
Comparing two ways to bypass cancer-caused stomach blockage

This trial compares two ways to bypass a stomach or intestinal blockage caused by cancer that cannot be cured with surgery. It tests a newer, less invasive procedure (endoscopic gastroenterostomy) against the standard surgical bypass (gastrojejunostomy) to see which works better for patients like you.

Nashville, Tennessee
NCT04641702Recruiting· Phase 4
Esophageal function study

This study looks at how well the esophagus works in people with swallowing problems, to improve diagnosis and treatment.

Atlanta, Georgia
NCT05735002Recruiting
Check tests to find chronic bowel blood flow problems early

This study looks at ways to promote early diagnosis of chronic mesenteric ischemia, a condition where the intestines don’t get enough blood over time. If you’re being evaluated for this problem, the trial may help ensure the right diagnosis happens sooner.

Enschede, Overijssel

Hear when a new Pseudo Obstruction trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.