Clin2
NCT07453576Possibly a fitRecruiting

Comparing bleach strengths for root canal retreatment pain

Persistent Apical Periodontitis

Part of Pain clinical trials.

This trial tests if different concentrations of sodium hypochlorite (a disinfectant used in root canals) affect pain and certain natural chemicals in the tooth during root canal retreatment. It may help find the best option to reduce discomfort.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
60 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You are between 18 and 65 years old.
  • You are generally healthy (no serious medical conditions).
  • You need a root canal retreatment on a tooth that has had a root canal before.
  • You have not taken painkillers, anti-inflammatory drugs, or antibiotics in the last 7 days.
  • You are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06509295Not yet recruiting
Comparing two root canal irrigants for pain and bacteria reduction

This study compares two root canal cleaning solutions (calcium hypochlorite vs. sodium hypochlorite) to see which one causes less pain and reduces bacteria better in lower premolars with dead nerves. If you have a tooth that needs a root canal and is not infected severely, you may qualify.

NCT07618182Not yet recruiting
Sodium Hypochlorite Concentration and Root Canal Pain

This study compares two different strengths of a cleaning solution used during root canal treatment to see which one causes less pain afterward. Root canal treatment cleans out infected or damaged tissue inside a tooth; this trial tests whether the cleaning solution's strength affects your pain recovery.

NCT07788027Recruiting
Comparing two root canal cleaning methods for reducing post-procedure discomfort

This study compares two different methods of delivering a cleaning solution during root canal treatment to see which one causes less pain and discomfort after the procedure. Participants will be randomly assigned to one of the two methods.

Minya
NCT07420920Not yet recruiting· Phase 1/Phase 2
Heated rinsing solution for root canal pain

This trial compares different ways of heating a special rinsing solution (sodium hypochlorite) inside a tooth during root canal treatment. The goal is to see which method works better at killing germs and reducing pain after the procedure. This study is for people who need a root canal on a single-rooted tooth that is already dead (no nerve pain).

NCT07453160Not yet recruiting
Root canal solutions: which causes less pain?

This study compares two root canal cleaning solutions (chlorhexidine and sodium hypochlorite) to see which one causes less pain after treatment. If you need a root canal and meet the health criteria, you may be able to help choose the gentler option.

NCT06959602Enrolling by invitation
Comparing two root canal cleaning methods for infected teeth

This trial compares two ways of cleaning infected root canals during a root canal procedure. The goal is to see which method better removes bacteria and improves healing.

Athens

Hear when a new Persistent Apical Periodontitis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.