DNA testing to guide treatment of bone infections after fracture surgery
Part of Infections clinical trials.
This study tests whether a special DNA test (called next-generation sequencing) can help doctors better identify and treat bone infections after fracture surgery. It compares this test to the usual culture method to see if it leads to better outcomes with antibiotics.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 84 years old.
- You had a broken bone in your arm or leg (not spine, hand, or foot) that was fixed with surgery using metal implants.
- After that surgery, you developed a deep infection that needed another surgery.
- Your doctor plans to treat you with antibiotics for this infection.
- You have not had a long-standing (chronic) infection at that site before.
- You are not at high risk of amputation and can have surgery safely.
- You can come to the study site for follow-up visits over the next 12 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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