Avelumab maintenance after second-line chemo for bladder cancer
Treatments studied
Part of Cancer clinical trials.
This trial tests whether a maintenance drug called avelumab can help keep metastatic bladder cancer from growing after patients have already responded to two prior treatments. It is for patients who had a specific sequence of therapies and whose cancer is stable after second-line chemotherapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had two specific treatments in order: first enfortumab vedotin plus pembrolizumab, then cisplatin or carboplatin plus gemcitabine for at least 3 cycles.
- Your cancer has not grown after that second-line chemo (it's stable or smaller).
- You are well enough to carry out daily activities with little or no help (ECOG 0 or 1).
- Your kidney function is adequate (creatinine clearance of at least 30 mL/min).
- No active autoimmune disease requiring high-dose steroids or other immune-suppressing drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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