Gemcitabine and carboplatin after EV-pembrolizumab for bladder cancer
Treatments studied
Part of Cancer clinical trials.
This trial tests a combination of two chemotherapy drugs, gemcitabine and carboplatin, for people whose bladder cancer has progressed after treatment with enfortumab vedotin plus pembrolizumab. The goal is to see if this chemo regimen can help control the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced (metastatic or locally advanced) bladder cancer that has spread or cannot be removed.
- Your cancer got worse after treatment with enfortumab vedotin plus pembrolizumab (EV-P) as your first therapy.
- You have not had more than one line of treatment for advanced disease, and you have not had platinum-based chemotherapy for advanced bladder cancer.
- You are able to get out of bed and care for yourself (ECOG score 0-2).
- Your blood counts and kidney/liver function are within certain safe limits (your doctor will check).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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