Comparing treatments for skin sores from leishmaniasis
Treatments studied
Part of Infections, Skin clinical trials.
This study compares different drugs to find the best one for treating cutaneous leishmaniasis, a skin infection that causes sores. You might get one of several treatments, and the goal is to see which works best and is safest for patients like you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed leishmaniasis infection (via lab test).
- You are between 4 and 65 years old.
- You need stronger treatment because you have multiple sores, a large sore (>4 cm), sores near your eyes/nose/lips, sores that didn't heal with local treatment, or deep sores that could cause disability.
- You haven't had any leishmaniasis treatment (like creams, injections, or pills) in the past 6 months.
- You are willing to stay in the hospital during treatment and come back for check-ups.
- You are not pregnant, breastfeeding, HIV-positive, or have serious health conditions (like heart, liver, kidney disease, or active infections like TB or hepatitis).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests how well miltefosine works for people with leishmaniasis, a skin infection from a parasite. It aims to find the best way to use this medicine to help patients get better.
This study tests if using heat therapy (thermotherapy) in local clinics is a good way to treat skin sores caused by leishmaniasis. It may be an option for people with a few small sores not on the face or near sensitive areas.
This study tests how your immune system responds to parts of a potential vaccine for leishmaniasis. Doctors will take small blood or skin samples to see if your body's cells react to these vaccine pieces, which could help design a better vaccine in the future.
This study tests two new oral medicines (called LXE408) against an existing oral treatment (miltefosine) for people with a first episode of localized cutaneous leishmaniasis (skin sores caused by a parasite). The goal is to see if the new medicines are safe and work better at healing the sores.
This study tests a gel containing miltefosine (a medicine) applied directly to the skin sores caused by cutaneous leishmaniasis. The goal is to see if the gel is safe and works to clear the sores.
This trial tests whether adding a special laser treatment (fractional CO₂ laser) to the standard injected medicine (Glucantime) helps heal skin sores from a parasite infection better than the medicine alone. It may offer a more effective way to clear the sores and improve healing.
Hear when a new Cutaneous Leihmaniasis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.