Leishmaniasis vaccine response study in Ethiopia
Part of Infections, Skin clinical trials.
This study tests how your immune system responds to parts of a potential vaccine for leishmaniasis. Doctors will take small blood or skin samples to see if your body's cells react to these vaccine pieces, which could help design a better vaccine in the future.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have symptoms of visceral leishmaniasis (like prolonged fever and enlarged spleen) or cutaneous leishmaniasis (like skin sores or nodules), OR you are a healthy volunteer living in Addis Ababa.
- You can understand and agree to the study procedures, and you are willing to provide informed consent.
- You are not pregnant, do not have other serious illnesses (like HIV, tuberculosis, or malaria), and have not taken immunosuppressive drugs, vaccines, or antileishmanial treatment in the past month.
- You are not on blood thinners and do not have bleeding disorders that could make blood or tissue sampling risky.
- For patients with skin lesions: your main skin sore is at least 2 cm in size, is in a location that can be safely sampled, and you are eligible for standard treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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