Genetic changes in tracheal narrowing with two treatments
Part of Lungs & breathing clinical trials.
This trial studies genetic changes in people with tracheal stenosis (narrowing of the windpipe). It compares two treatments: wedge resection (cutting out the narrow part) and radial incision (cutting to open it up). This may help doctors choose the best treatment in the future.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have narrowing in your windpipe (tracheal stenosis) that causes symptoms like trouble breathing
- Your narrowing is either from an unknown cause (idiopathic subglottic stenosis), or from having a breathing tube or trach
- You do not have certain autoimmune conditions (positive ANA or ANCA blood test)
- Your narrowing is not from an infection like tuberculosis, cancer, a benign tumor, or a broken cartilage piece
- You do not have a soft or floppy windpipe (malacia), and the narrowing is not in your vocal cord area or above
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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