Testing brain stimulation and rewards for quitting cocaine
Part of Mental health clinical trials.
This trial combines deep transcranial magnetic stimulation (TMS) with a reward program (contingency management) to help people stop using cocaine. It may help if you are struggling with moderate to severe cocaine use and want a non-drug treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and have been using cocaine regularly (tested positive on a urine drug screen).
- You are willing to come to the study for TMS sessions and urine tests, and give contact info for 2 people who can reach you.
- If you are female and able to get pregnant, you must use birth control (like pills, IUD, or abstinence) and have a negative pregnancy test before starting.
- You do not have other serious substance use disorders (like alcohol or opioids) needing detox, or unstable mental health conditions (like psychosis, bipolar disorder, or recent suicidal thoughts).
- You do not have medical implants (like pacemaker, metal clips, or stimulators) or conditions that prevent MRI or TMS (like epilepsy, recent head injury, or severe heart disease).
- You are not taking certain medications that raise seizure risk (like bupropion, clozapine, or other stimulants) within 1 week of the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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