Surgery and heated chemotherapy for pancreatic cancer with spread to the abdomen
Treatments studied
Part of Cancer, Digestive system, Hormones & metabolism clinical trials.
This trial tests if combining surgery to remove the tumor with a special heated chemotherapy bath for the abdomen (HIPEC) is safe and possible for people whose pancreatic cancer has spread only to the lining of the abdomen.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with pancreatic adenocarcinoma, a type of pancreatic cancer.
- The cancer has spread only to the lining of your abdomen (peritoneum), not to other organs (like the liver or lungs).
- The amount of cancer in your abdomen is small (a PCI score of 6 or less).
- You are older than 18 years.
- You are in good general health, able to care for yourself (ECOG score 0 or 1).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests a treatment that combines heating chemotherapy drugs and delivering them directly into the abdomen (HIPEC) with standard chemotherapy through a vein. It is for people whose pancreatic cancer has spread to the lining of the abdomen but not to other organs, and who have not had prior cancer treatment.
This trial tests a treatment called HIPEC (heated chemotherapy given directly into the abdomen during surgery) for stomach cancer that has spread to the lining of the belly. The goal is to see if this approach can help remove or shrink the cancer and improve outcomes.
This trial tests giving heated chemotherapy directly into the belly during surgery for stomach cancer. It might help people with cancer that has spread to the lining of the belly but not to other organs.
This trial tests a combination of treatments for stomach cancer that has spread to the lining of the abdomen. The goal is to see if this approach can shrink or control the cancer, potentially making surgery possible.
This trial tests a treatment for pancreatic cancer that has spread to the liver (with no more than a few liver tumors). Patients will receive chemotherapy plus surgery and a heat-based procedure (thermal ablation) to destroy the liver tumors. The goal is to see if combining these treatments helps control the cancer better than chemotherapy alone.
This study looks at adding a heated medicine treatment (HIPEC with mitomycin C) during surgery to treat colon cancer that has spread to the lining of the abdomen (peritoneum). It aims to improve outcomes after surgeons remove visible tumor completely.
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