Surgery and heated chemotherapy for pancreatic cancer with spread to the abdomen
Treatments studied
Part of Cancer, Digestive system, Hormones & metabolism clinical trials.
This trial tests if combining surgery to remove the tumor with a special heated chemotherapy bath for the abdomen (HIPEC) is safe and possible for people whose pancreatic cancer has spread only to the lining of the abdomen.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with pancreatic adenocarcinoma, a type of pancreatic cancer.
- The cancer has spread only to the lining of your abdomen (peritoneum), not to other organs (like the liver or lungs).
- The amount of cancer in your abdomen is small (a PCI score of 6 or less).
- You are older than 18 years.
- You are in good general health, able to care for yourself (ECOG score 0 or 1).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a treatment that combines heating chemotherapy drugs and delivering them directly into the abdomen (HIPEC) with standard chemotherapy through a vein. It is for people whose pancreatic cancer has spread to the lining of the abdomen but not to other organs, and who have not had prior cancer treatment.
This Phase 2 study tests a treatment that warms chemotherapy and delivers it directly into the abdomen to treat pancreatic cancer that has spread to the lining of the belly (peritoneum). You may be eligible if you completed earlier chemotherapy and your body shows signs the cancer is responding, with limited spread in the abdomen.
This trial tests giving heated chemotherapy directly into the belly during surgery for stomach cancer. It might help people with cancer that has spread to the lining of the belly but not to other organs.
This study looks at adding a heated medicine treatment (HIPEC with mitomycin C) during surgery to treat colon cancer that has spread to the lining of the abdomen (peritoneum). It aims to improve outcomes after surgeons remove visible tumor completely.
This trial tests a treatment called PIPAC, where chemotherapy is sprayed as a mist into the abdomen during a minimally invasive surgery. It is for people whose pancreatic cancer has spread to the lining of the belly, and aims to see if this approach is safe and helpful.
This trial compares standard laparoscopic surgery for stomach cancer versus the same surgery plus HIPEC, which is heated chemotherapy placed in the abdomen during the operation. It aims to see if adding the heated chemotherapy improves outcomes for people with higher-stage stomach cancer.
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