Melatonin gel for pain relief in root canal treatment
Treatments studied
Part of Mouth & dental, Pain clinical trials.
This trial tests if a melatonin gel placed inside the tooth can reduce pain after root canal treatment. It compares melatonin to the standard calcium hydroxide paste. The goal is to see which works better for pain, bacterial reduction, and tissue healing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age between 18 and 50 years old.
- You must be in good general health (classified as ASA I or II).
- You have a lower premolar tooth with one root that is dead (necrotic pulp).
- You can understand and rate your pain on a scale, and you agree to join the trial.
- You have not taken painkillers or antibiotics in the past 24 hours.
- The tooth has not been treated before, is fully formed, and has no abscess, swelling, or severe gum disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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