Melatonin gel versus calcium hydroxide for reducing tooth pain
Treatments studied
Part of Mouth & dental clinical trials.
This trial tests whether a melatonin gel placed inside the tooth can reduce pain and infection better than a standard calcium hydroxide paste after root canal treatment. It may help people with an infected, dead tooth feel less pain after the procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 50 years old.
- You have a lower premolar tooth (a tooth just behind the canine) that is fully dead (needs root canal).
- You are generally healthy (any chronic conditions are mild and well-controlled).
- You have not taken painkillers or antibiotics in the last 24 hours.
- You are not pregnant.
- You do not have bruxism (teeth grinding), clenching, or jaw joint problems.
- You have not had a root canal on that tooth before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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