How Urolithin A Moves Through the Brain and Spinal Fluid
This study tracks how a natural compound called Urolithin A travels through your brain and spinal fluid after you take it. Researchers want to understand how this substance moves in the body, which could help them develop treatments for brain health in the future.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 45 years old and in generally good health
- Have a normal heart rhythm (ECG) and chest X-ray, or any findings judged not medically important
- Not smoke, or smoke no more than 5 cigarettes per day
- Have a BMI (body weight ratio) between 18.5 and 30.0
- Avoid specific supplements and foods (like pomegranate, resveratrol, certain vitamins) for 2 weeks before and during the study
- Be willing to stay overnight at a research facility, fast for 14+ hours, and undergo blood draws and lumbar puncture (spinal fluid collection)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a substance called urolithin A can be detected using dried blood spots (small samples on a card). It also checks whether people can safely take the study product and complete questionnaires during the study.
This trial tests whether a daily supplement called Urolithin A (Mitopure®) can improve muscle strength in healthy middle-aged adults who are not very active. Researchers will measure changes in strength and fitness over several weeks.
This study tests if a natural supplement called Urolithin A can help improve how your body handles sugar (glucose) in healthy adults aged 55 and older who have a higher body weight. You would take a daily capsule and come in for tests including blood work, treadmill walks, and an MRI.
This trial tests whether taking a supplement called urolithin A can help people with a BMI over 30 lose weight while following a personalized diet and exercise program. The study also looks at changes in fat, muscle, and sleep.
This trial tests adding a natural supplement called urolithin A to standard first-line immunotherapy for people with newly diagnosed solid tumors who have not yet had any cancer treatment. The goal is to see if it makes the immunotherapy work better.
This study tests a single dose of LG-0317 tablets to see how much of the brain's serotonin transporter it occupies. It uses PET/CT scans and is for healthy men only. Results will help understand how the drug works in the brain.
Hear when a new Healthy Adult trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.