Clin2
NCT07527442Possibly a fitNot yet recruiting

Circumcision to prevent urinary infections in newborn boys with posterior urethral valves

Posterior Urethral Valves

Part of Infections, Kidney & urinary clinical trials.

This study tests whether circumcision alone can reduce the risk of urinary tract infections with fever in newborn boys who have posterior urethral valves, a birth defect that can block urine flow. It compares circumcision alone to standard care, and aims to see if it helps prevent these infections.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
72 people
Ages
1 day to 1 month
Study type
Interventional

Who can take part

  • Your baby is a boy, between 1 and 31 days old.
  • Your baby has posterior urethral valves, diagnosed within the first 28 days of life.
  • Your baby will have valve surgery and circumcision before 1 month of age.
  • You are a parent or guardian over 18 years old and can give informed consent.
  • You are covered by a social security system (for the prospective group).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06439862Recruiting
Quality of life in children with posterior urethral valves

This study looks at how children with posterior urethral valves (a condition that affects urination) feel about their quality of life as they grow up. It will help doctors understand how these children are doing emotionally and socially, so they can improve care.

Bron, Bron
NCT07508124Recruiting· Phase 4
Steroid cream to prevent repeat UTIs in uncircumcised baby boys

This study tests if a steroid cream applied to the foreskin can help prevent another urinary tract infection (UTI) in uncircumcised baby boys under 6 months old who have already had one confirmed UTI.

Houston, Texas
NCT04526353Recruiting· Phase 2
Oxybutynin for young boys with posterior urethral valves

This trial tests whether early use of oxybutynin can improve bladder and urine behavior in very young boys with posterior urethral valves. It is mainly for babies whose bladder tests show problems even after valve surgery.

Bordeaux
NCT06737016Recruiting· Phase 3
Testing tamsulosin for children with posterior urethral valve

This trial tests if tamsulosin, a medicine that relaxes muscles in the bladder and prostate, can help children with a condition called posterior urethral valve. It aims to improve how the bladder works and reduce urinary problems.

Al Mansurah, Dakahlia Governorate
NCT04846803Recruiting
Prevent repeat UTIs using bacterial interference treatments

This trial studies a new way to help stop urinary tract infections (UTIs) from coming back by using “bacterial interference” (changing the bacteria in the urinary system). It may help people who have had UTIs keep returning despite past treatments.

Aarhus N
NCT07206992Not yet recruiting
Antibiotics before urological endoscopy for patients with bacteria in urine

This trial tests whether taking antibiotics for 24 hours before urological endoscopic surgery reduces the risk of infection in patients who have bacteria in their urine but no symptoms. It may help prevent complications after the procedure.

Paris

Hear when a new Posterior Urethral Valves trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.