Guselkumab for Crohn's Disease After Bowel Surgery
Treatments studied
Part of Digestive system clinical trials.
This study tracks how well a medication called guselkumab works for people with moderate to severe Crohn's disease who have had surgery to remove part of their intestines. Researchers want to see if this treatment helps prevent the disease from coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have been diagnosed with moderate to severe Crohn's disease
- You have had surgery to remove part of your small intestine and colon (called ileocolonic resection)
- You do not have short bowel syndrome (a condition where too much intestine was removed)
- You do not currently have an infection or abscess (a pocket of infection)
- You have not been diagnosed with cancer in the last 5 years
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at whether guselkumab, a different biologic medicine, can help people with Crohn's disease who have already tried ustekinumab but it didn't work well or caused side effects. It aims to see if switching to guselkumab is safe and effective.
This study compares two medicines, Guselkumab and Ustekinumab, for people with Crohn's disease that causes narrowing (strictures) in the bowel. It aims to find which works better to improve symptoms and avoid the need for more procedures.
This trial compares different biologic medications to see which best prevents Crohn's disease from coming back after intestinal surgery. It may help you if you have had surgery for Crohn's and are starting a biologic drug soon after.
This study tests guselkumab, a medication that reduces inflammation in the gut, for people with moderate-to-severe Crohn's disease or ulcerative colitis who haven't previously tried certain similar biologic drugs. The goal is to see how well it works and is tolerated in real-world use.
This study tests whether guselkumab (a targeted drug) can effectively treat Crohn's disease in the ileum (last part of the small intestine). You will have ultrasound scans and blood tests to measure your response, which may help find the right dose and monitor for bowel healing.
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