Aspirin for preventing liver cancer in people with cirrhosis
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial is testing whether taking a low dose of aspirin every day can lower the risk of developing liver cancer (hepatocellular carcinoma, or HCC) in people with liver cirrhosis. Liver cirrhosis is scarring of the liver, and having it increases the risk of liver cancer. If you are eligible, you would be asked to take aspirin or a placebo (a pill with no active medicine) and have regular check-ups to see if aspirin helps prevent cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had liver cirrhosis for at least 6 months.
- Your liver disease is stable (not causing symptoms like fluid buildup or confusion).
- You have had a liver ultrasound, CT scan, or MRI in the past 6 months as part of liver cancer screening.
- No suspicious spots (other than benign hemangiomas) were seen on your liver imaging in the last 6 months.
- You are not currently taking aspirin, blood thinners, or certain pain relievers, and you haven't taken them in the last 6 months.
- You do not have serious bleeding risk factors like a bleeding disorder, stomach ulcers, or enlarged veins in your throat or stomach that have bled.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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