Combination treatment for pustules on palms and soles
Treatments studied
Part of Skin clinical trials.
This trial tests a combination of two drugs (tofacitinib and imatinib) for people with moderate-to-severe palmoplantar pustulosis, a painful skin condition affecting the palms and soles. The goal is to see if this combo can reduce pustules and improve symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You must have a confirmed diagnosis of palmoplantar pustulosis (PPP) for at least 12 weeks.
- Your PPP must be moderate to severe, based on a skin score (PPPASI) of at least 12.
- You must have active pustules on your palms or soles at the time of screening.
- You must not have certain other skin conditions, such as hand eczema or generalized pustular psoriasis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new oral medication, ivarmacitinib, for adults with palmoplantar pustulosis (PPP) who haven't gotten better with standard treatments. It aims to see if the drug is safe and effective for reducing the painful pustules on the palms and soles.
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This trial tests a cream called delgocitinib for people with mild to severe palmoplantar pustulosis (PPP), a skin condition with pustules on the palms and soles. The cream is applied daily for 16 weeks to see if it improves symptoms and is safe.
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