Combination treatment for rheumatoid arthritis
Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.
This study tests whether combining two medicines, iguratimod and tofacitinib, works better than taking either alone for people with rheumatoid arthritis whose symptoms are not well controlled by their current treatment. If you join, you might get both drugs together to see if it helps reduce pain and swelling.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You must have a confirmed diagnosis of rheumatoid arthritis.
- You must have tried at least one standard treatment (like methotrexate, a biologic, or tofacitinib) for at least 3 months and still have moderate to high disease activity.
- You cannot be allergic to iguratimod or tofacitinib.
- You cannot have active infections, HIV, hepatitis B or C, an active or latent tuberculosis infection, or severe heart failure.
- You must be willing to sign a consent form to participate.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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