Liver enzyme changes in pregnant women with hepatitis B
Part of Digestive system, Infections, Women’s health & pregnancy clinical trials.
This study tracks pregnant women with hepatitis B to understand why some develop elevated liver enzymes after delivery and what factors predict this. Findings could help doctors better monitor and care for mothers with hepatitis B during and after pregnancy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Female, age 20–40 years old
- Hepatitis B surface antigen (HBsAg) positive for at least 6 months
- Normal liver enzyme (ALT) level at start: 40 U/L or lower
- Currently pregnant (between 24 weeks of pregnancy and delivery)
- If hepatitis B virus level is very high (>200,000 IU/ml), must take tenofovir (TDF) antiviral medication during pregnancy and stop it immediately after delivery
- No other liver infections (hepatitis A, C, E), liver disease, heart/lung/kidney disease, or autoimmune conditions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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