Testing a gut-healing injection for undernourished women
Part of Digestive system, Hormones & metabolism clinical trials.
This study tests a drug called teduglutide (a lab-made version of a natural gut hormone) to see if it can heal gut damage in undernourished women. If you don't improve with just food supplements, you may be given this injection for a month to help your gut work better and absorb more nutrients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman between 18 and 35 years old and live in Bangladesh.
- You are underweight, with a body mass index (BMI) between 16 and 18.5, and have been diagnosed with a gut condition called environmental enteric dysfunction (EED), which can make it hard to absorb nutrients.
- You have not taken antibiotics in the last month.
- You are willing to take a daily injection of a study drug (teduglutide) for 1 month, and to take food supplements and extra vitamins for 2 months.
- You are willing to have an endoscopy (a tube with a camera put into your stomach to take small tissue samples) twice during the study.
- You are willing to give blood and other samples over the 4-month study, and you must not be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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