Cell injection for treating anal fistulas
Part of Digestive system clinical trials.
This study tests an experimental cell-based injection to help heal a type of anal fistula (an abnormal tunnel between the bowel and skin near the anus). It may be an option for people whose fistula is simple, not caused by Crohn's disease, and not currently infected or painful.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You must have a single anal fistula (a tunnel between the bowel and the skin near the anus) that is simple, not branching, and not connected to the vagina (for women).
- Your fistula must not be caused by inflammatory bowel disease (like Crohn's disease or ulcerative colitis).
- You must not have an active infection, abscess, or significant fistula pain (score less than 3 on a 0–10 pain scale).
- You must not have severe kidney or liver problems, bleeding disorders, or be taking steroid medication within the last month.
- You must agree to use effective birth control (if applicable) and avoid pregnancy or donating sperm during the study and for 3 months after treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 1 study tests whether a donated-cell treatment (given with a minor procedure) can help heal simple anal fistulas. It mainly focuses on safety first, but may also look at how well the fistula closes.
This trial tests a new treatment made from special cells (called E-CEL UVEC) for people with long-lasting anal fissures that haven't healed with standard treatments. The goal is to see if this cell-based therapy can reduce pain and help the fissure heal.
This trial tests a new cell injection (TH-SC01) to treat anal fistulas caused by Crohn's disease. It aims to see if the injection can heal fistulas and lower infection risk.
This trial tests whether injecting your own fat-derived cells combined with a skin graft can heal anal fistulas (abnormal passages near the anus) that didn't respond to or came back after a previous cell therapy study. You must have already participated in the ADICROHN-2 study.
This trial tests a hydrogel made from natural materials to help heal a specific type of anal fistula. It may be an option if you have a single high transsphincteric fistula with a seton in place for at least four weeks.
This trial tests if a special stem cell treatment (called DB-3Q bmMSC-EVs) can help heal fistulas caused by Crohn's disease. It's for people who have already tried other treatments and still have actively draining fistulas.
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