Cell Injection Treatment for Perianal Fistulas
Part of Digestive system clinical trials.
This trial tests a new cell-based treatment (E-CEL UVEC cells) injected directly into perianal fistulas—abnormal tunnels near the anus that can cause pain and drainage. The goal is to help these fistulas heal without surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 or older
- Diagnosed with a single perianal fistula confirmed by MRI or ultrasound, with specific characteristics (low-level tract, less than 10 cm long, less than 3 mm opening)
- Mild fistula pain (score less than 3 on a 0–10 pain scale)
- No inflammatory bowel disease (Crohn's disease or ulcerative colitis)
- Healthy kidney and liver function based on blood tests
- Not pregnant, breastfeeding, or planning to become pregnant during the 3–6 month study period
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 1 study tests whether a donated-cell treatment (given with a minor procedure) can help heal simple anal fistulas. It mainly focuses on safety first, but may also look at how well the fistula closes.
This trial tests a new treatment made from special cells (called E-CEL UVEC) for people with long-lasting anal fissures that haven't healed with standard treatments. The goal is to see if this cell-based therapy can reduce pain and help the fissure heal.
This trial tests a new cell injection (TH-SC01) to treat anal fistulas caused by Crohn's disease. It aims to see if the injection can heal fistulas and lower infection risk.
This trial tests if a special stem cell treatment (called DB-3Q bmMSC-EVs) can help heal fistulas caused by Crohn's disease. It's for people who have already tried other treatments and still have actively draining fistulas.
This trial tests a hydrogel made from natural materials to help heal a specific type of anal fistula. It may be an option if you have a single high transsphincteric fistula with a seton in place for at least four weeks.
This trial tests whether injecting your own fat-derived cells combined with a skin graft can heal anal fistulas (abnormal passages near the anus) that didn't respond to or came back after a previous cell therapy study. You must have already participated in the ADICROHN-2 study.
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