Cell therapy for Crohn's disease fistulas after prior treatment
Part of Digestive system clinical trials.
This trial tests whether injecting your own fat-derived cells combined with a skin graft can heal anal fistulas (abnormal passages near the anus) that didn't respond to or came back after a previous cell therapy study. You must have already participated in the ADICROHN-2 study.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Crohn's disease diagnosed at least 6 months ago
- You were enrolled in or treated in the ADICROHN-2 study
- You either didn't respond to that prior treatment or your fistulas came back
- Your Crohn's disease is currently not very active (mild symptoms at most)
- You have enough frozen cells from the prior study available for treatment
- You are 18 or older, in generally good health, and able to use contraception if needed
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new, less invasive procedure called regenerative endoscopy to repair complex fistulas in people with Crohn's disease. It's for those who haven't gotten better with standard treatments like biologics or surgery.
This Phase 2 trial studies whether a local injection of fat-derived cells (made from your own tissue) can improve difficult Crohn’s disease fistulas around the anus. It’s designed for people whose Crohn’s fistulas have not responded to usual treatments.
This trial tests a new cell injection (TH-SC01) to treat anal fistulas caused by Crohn's disease. It aims to see if the injection can heal fistulas and lower infection risk.
This trial tests whether injecting donated stem cells into complex anal fistulas can help heal them in people with Crohn's disease. You may qualify if you have a fistula that hasn't improved with standard treatments.
This trial tests if a special stem cell treatment (called DB-3Q bmMSC-EVs) can help heal fistulas caused by Crohn's disease. It's for people who have already tried other treatments and still have actively draining fistulas.
This trial tests a new approach that combines traditional Chinese medicine with stem cells to treat complex anal fistulas caused by Crohn's disease. It may help people whose Crohn's is not very active and who have not had major fistula surgery before.
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