Preventing Hand-Foot Skin Reaction in Liver Cancer Treatment
Part of Cancer, Digestive system clinical trials.
This study tests whether a topical anti-inflammatory cream (indomethacin) applied preventively to hands and feet can reduce a painful skin side effect called hand-foot syndrome that occurs in advanced liver cancer patients taking sorafenib. If effective, it could help patients tolerate their cancer medication better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced liver cancer (hepatocellular carcinoma) that has spread or hasn't responded to other treatments
- Your doctor believes sorafenib is an appropriate treatment for you
- You are 18 or older and able to give informed consent
- Your liver function is well-preserved (Child-Pugh score A or B7)
- You are in reasonably good health overall (ECOG performance status of 2 or better)
- If you can have children, you agree to use contraception during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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