Ampicillin With or Without Gentamicin for Water Bag Rupture at Term
Treatments studied
Part of Genetic & congenital, Infections, Women’s health & pregnancy clinical trials.
This trial tests two antibiotic approaches for pregnant women at term (37+ weeks) whose water bag has broken. Researchers are comparing ampicillin alone versus ampicillin plus gentamicin to see which approach better prevents infection and leads to better outcomes for mother and baby.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old and carrying one baby (singleton pregnancy)
- Your pregnancy is at 37 weeks or more, and your baby is head-down (vertex presentation)
- Your water bag broke 12 hours or less ago, confirmed by your doctor
- You don't have a fever, no signs of infection, and clear fluid (not stained with meconium/baby's first stool)
- You haven't already taken antibiotics for this pregnancy or in the past 7 days
- You plan to deliver at a hospital participating in this study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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