Antibiotic options for preterm membrane rupture
Treatments studied
Part of Genetic & congenital, Women’s health & pregnancy clinical trials.
This trial compares different antibiotics given to pregnant people whose waters break early (before 37 weeks) to prevent infection and improve outcomes. It aims to find the most effective antibiotic to protect both the parent and the baby.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at risk of giving birth before 37 weeks of pregnancy
- Your waters have broken early (preterm prelabour rupture of membranes) before 37 weeks, confirmed by a doctor
- You have not already been on antibiotics for this condition for more than 24 hours
- You do not have a current infection in the womb (chorioamnionitis) or need immediate delivery
- You are not in active preterm labour (cervix dilated 3 cm or more with regular contractions)
- You or your baby are not affected by a major congenital abnormality, and you have not had a previous baby with group B strep infection
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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