Alpha-Lipoic Acid to Protect Kidneys During Cisplatin Cancer Treatment
Treatments studied
Part of Cancer, Kidney & urinary clinical trials.
This study tests whether a supplement called alpha-lipoic acid can help protect your kidneys from damage caused by cisplatin, a common chemotherapy drug. If it works, it could reduce side effects and help you tolerate your cancer treatment better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old
- You have been diagnosed with a solid tumor (cancer) confirmed by biopsy
- Your doctor plans to treat you with cisplatin chemotherapy at a standard dose
- Your kidneys are working normally (measured by creatinine and glomerular filtration rate tests)
- You are able to take care of yourself or need minimal help (ECOG performance status 0–2)
- You are not pregnant, not breastfeeding, and not allergic to alpha-lipoic acid
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether taking vitamin C and coenzyme Q10 can help protect your kidneys while you receive chemotherapy with cisplatin and gemcitabine. It may reduce the risk of kidney damage from these treatments.
This trial tests whether taking alpha lipoic acid (an antioxidant) alongside the antibiotic colistin can help protect the kidneys from damage. It may be helpful for patients who need colistin to fight a serious bacterial infection.
This trial tests if a supplement called L-carnitine can help prevent kidney damage caused by the chemotherapy drug cisplatin. It may be an option for newly diagnosed cancer patients who need cisplatin treatment.
This trial tests a way to protect your kidneys while you receive platinum-based chemotherapy (cisplatin or carboplatin) for a solid tumor. It may help reduce the risk of kidney damage so you can complete your treatment more safely.
This trial tests an injection called GMDTC to see if it can protect the kidneys in people who already have mild kidney problems from cisplatin chemotherapy and need more cisplatin. It aims to reduce further kidney damage while continuing cancer treatment.
This study tests whether a natural supplement made from citrus plant compounds (diosmin and hesperidin) can protect your kidneys from damage caused by platinum-based chemotherapy drugs. Platinum chemotherapy is effective against many cancers but can harm kidney function over time.
Hear when a new Nephrotoxicity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.