Leflutrozole for male infertility with no sperm
Part of Kidney & urinary clinical trials.
This trial tests whether a new hormone medication called leflutrozole can help men with azoospermia (no sperm in semen) produce sperm again. The medication works by adjusting hormone levels to stimulate sperm production.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 55 years old
- Have azoospermia (zero sperm) confirmed by at least 2 semen tests, with no blockage in your reproductive tract
- Have specific hormone levels within range (low testosterone, normal or high estradiol, and detectable AMH or Inhibin B)
- Not have genetic conditions like Klinefelter syndrome or major sex chromosome problems
- Not be taking most prescription medications (except vitamins and over-the-counter pain relievers)
- Not have serious heart disease, blood clots, bone loss, or uncontrolled chronic conditions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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