Papaverine treatment for chemo nerve damage
Part of Brain & nervous system, Cancer clinical trials.
This study tests whether papaverine, a blood vessel-relaxing medication, can reduce nerve pain and numbness caused by taxane chemotherapy drugs. You may qualify if you've completed chemotherapy at least 4 weeks ago and nerve symptoms haven't improved with standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18–75 years
- Finished taxane chemotherapy (paclitaxel, docetaxel, or similar) at least 4 weeks ago
- Have moderate to severe nerve pain/numbness in hands or feet from chemotherapy
- Tried at least one standard nerve pain medication for 4+ weeks without relief or couldn't tolerate it
- Healthy enough liver and kidney function to safely take the study drug
- Nerve symptoms must be mainly from chemotherapy, not diabetes, vitamin deficiency, or other causes
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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