Study of EPN-701 for calciphylaxis pain
Part of Hormones & metabolism clinical trials.
This trial tests an investigational drug called EPN-701 for people with calciphylaxis, a painful condition that causes skin ulcers and often affects those on dialysis. The study aims to see if the drug can reduce pain and improve the condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a confirmed diagnosis of calciphylaxis with at least one open sore (ulcer) and moderate to severe pain (score of 5 or more on a 0–10 pain scale).
- You must be on hemodialysis three times a week (not peritoneal dialysis).
- You must be 18 years or older.
- If you are a woman who could become pregnant, you must use highly effective birth control and a barrier method, and have a negative pregnancy test.
- Men who are sexually active must use condoms, and all participants must agree not to donate sperm or eggs during the study.
- You cannot be in hospice care, have a serious liver disease (cirrhosis), or have had cancer (except certain minor skin or cervical cancers) in the past year.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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