Testing a cholesterol drug to lower PFAS in veterans
Treatments studied
Part of Hormones & metabolism clinical trials.
This study tests whether a medication called colesevelam, which is normally used to lower cholesterol, can help reduce the levels of PFAS (forever chemicals) in your blood. PFAS are harmful chemicals that stick around in the body, and this trial aims to see if the drug can help remove them, potentially lowering your risk of health problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a Veteran between 25 and 65 years old.
- Your blood test shows PFAS (forever chemicals) above 20 ng/ml, which is higher than what experts suggest is safe.
- You are willing to give written permission to join and to share your health data and blood samples for research.
- You are not pregnant, nursing, or planning pregnancy during the study.
- You do not have certain health issues like high triglycerides, vitamin deficiency, overactive thyroid, diabetes, pancreatitis, or bowel blockage.
- You are not currently taking other investigational drugs or participating in other research studies.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if taking a special tablet twice daily can help male firefighters lower PFAS chemicals in their bodies. It involves three visits in the San Francisco Bay Area, at-home blood tests, and weekly text surveys over about 6.5 months.
This study looks at using a genetic test to help doctors choose the best statin medicine for veterans who need to lower their cholesterol but haven't taken a statin in the last 6 months. If you have diabetes, heart disease, or have had a stroke, this trial may help find a statin that works well for you with fewer side effects.
This trial tests if a new medicine, lerodalcibep, can safely lower cholesterol in children ages 6 to 17 who have a genetic condition called heterozygous familial hypercholesterolemia (HeFH). It aims to help children whose cholesterol stays high despite taking standard cholesterol-lowering drugs.
This trial tests whether a daily dietary supplement can reduce levels of PFAS chemicals in the blood. If you are a male firefighter with past exposure to PFAS, this study might help you lower these chemicals.
This study looks at how PFAS chemicals in tap water may affect health. If you join, researchers will check your PFAS levels and see if a treatment can help lower them.
This study tests an experimental drug (QLC7401) that may help lower LDL ('bad') cholesterol in people who already have high cholesterol or mixed hyperlipidemia. If you're on stable cholesterol medication but still need more lowering, this trial could offer another option.
Hear when a new Burn Pit Exposure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.