Immune System Treatment to Help Down Syndrome Development
Treatments studied
Part of Brain & nervous system, Genetic & congenital clinical trials.
This study tests a medication called tofacitinib that modulates the immune system in children and young adults with Down syndrome aged 6–22 years. The goal is to see if it can improve brain development and overall health outcomes over 6 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 6 to 22 years old with Down syndrome (any type)
- Parent or guardian available to sign consent and complete study materials
- Body weight of at least 10 kg (about 22 lbs)
- No recent treatment with JAK inhibitors or other experimental agents in the past 3 weeks
- No active serious infections, blood clots, or cancer history
- Able to have repeated blood tests and complete developmental assessments
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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