Understanding enlarged rectum and chronic constipation
Part of Digestive system clinical trials.
This research study compares two groups of adults with long-term constipation: those with an enlarged rectum (megarectum) and those without. Researchers will study how the rectum works differently in each group to better understand what causes severe constipation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have chronic constipation (long-lasting difficulty with bowel movements) that meets medical diagnostic criteria
- You are willing to have specialized tests: anorectal manometry (a tube measuring rectal muscle function) and rectal barostat (a balloon test measuring rectal sensitivity)
- You do not have Hirschsprung's disease, anorectal birth defects, or known neurological conditions
- You are not taking medications known to cause constipation (like morphine or antipsychotics)
- You can complete questionnaires about your symptoms and medical history
- You are legally able to provide informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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