Clin2
NCT07599800Possibly a fitNot yet recruiting

Topical spray for shingles nerve pain

PHN - Post-Herpetic Neuritis

Part of Infections, Pain clinical trials.

This trial tests a new medicated spray, APC101, applied directly to the skin to reduce the burning and stabbing pain of postherpetic neuralgia (pain after shingles). The study lasts about 6 months and compares the spray to a placebo (inactive version) to see if it is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
333 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You have had pain in the area where you had shingles for more than 3 months after the rash healed.
  • Your average pain in the past week is 5 or higher on a 0 to 10 scale.
  • The skin over the painful area must be intact and not near any moist areas like the eyes or mouth.
  • If you take pain medicines, they must be stable for 30 days and you must be willing to keep the same dose during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07565844Recruiting
Injected treatments for nerve pain after shingles

This trial tests three injected treatments—tiny cell particles, platelet-rich plasma, and steroids—directly into the skin to reduce long-lasting nerve pain that follows shingles. If you've had persistent shingles pain for at least 3 months, this study may help ease your discomfort.

Zagazig, Zagazig
NCT06959147Recruiting· Phase 4
Study for nerve pain after shingles using radiofrequency and a numbing shot

This trial tests a two-step procedure for treating nerve pain after shingles (called postherpetic neuralgia). First, a special type of radiofrequency treatment is applied to block the pain signals. Then, a long-lasting numbing medicine is injected under the skin to help keep the pain away. It is for people aged 40 to 85 who have not gotten enough relief from standard medicines.

Zunyi, Guizhou
NCT07352553Not yet recruiting
Brain stimulation for long-lasting shingles pain

This trial tests a pain-relieving brain stimulation treatment for people with long-lasting pain after shingles (called postherpetic neuralgia). It compares the real treatment to a sham (inactive) procedure to see if it truly reduces pain.

Wuhan, Hubei
NCT06978192Recruiting· Phase 2
Study for treating shingles pain with a special nerve block

This trial tests a combination of two treatments to reduce shingles pain that hasn't responded to standard medicines. It involves a nerve block to see if it can help people who have ongoing pain after shingles.

Zunyi, Guizhou
NCT07390279Recruiting
Radiofrequency treatment for shingles-related nerve pain

This study tests a safe, non-surgical treatment called transcutaneous pulsed radiofrequency to see if it can help reduce nerve pain that continues after shingles. It targets the painful area through pads on the skin.

Istanbul, Istanbul
NCT06990854Not yet recruiting
Electroacupuncture for nerve pain after shingles

This study tests whether electroacupuncture (a type of acupuncture using mild electric pulses) can reduce nerve pain after shingles. It also looks for biomarkers to see how the treatment works.

Hangzhou, Zhejiang

Hear when a new PHN - Post-Herpetic Neuritis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.