Brain stimulation for long-lasting shingles pain
Part of Brain & nervous system, Pain clinical trials.
This trial tests a pain-relieving brain stimulation treatment for people with long-lasting pain after shingles (called postherpetic neuralgia). It compares the real treatment to a sham (inactive) procedure to see if it truly reduces pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have had shingles and the pain has lasted for at least 3 months.
- Your pain is a 4 or higher on a 0-10 scale.
- You are willing to try the treatment and sign a consent form.
- You do not have metal in your head or a pacemaker, and you are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a treatment called peripheral nerve stimulation (using a small device to send mild electrical pulses) for people with nerve pain after shingles. It's designed for those whose pain is not well managed by usual treatments.
This study tests a safe, non-surgical treatment called transcutaneous pulsed radiofrequency to see if it can help reduce nerve pain that continues after shingles. It targets the painful area through pads on the skin.
This study tests a combination of two treatments for long-term nerve pain after shingles: a medication called esketamine and a nerve block (pulsed radiofrequency) applied to the affected spinal nerves. The goal is to see if this combination relieves the burning or shooting pain better than the nerve block alone.
This trial tests whether adding esketamine to two standard pain medicines (pregabalin and duloxetine) can better treat nerve pain from shingles that persists for months. It's for people whose pain hasn't improved enough with pregabalin alone.
This trial tests a two-step procedure for treating nerve pain after shingles (called postherpetic neuralgia). First, a special type of radiofrequency treatment is applied to block the pain signals. Then, a long-lasting numbing medicine is injected under the skin to help keep the pain away. It is for people aged 40 to 85 who have not gotten enough relief from standard medicines.
This trial tests three injected treatments—tiny cell particles, platelet-rich plasma, and steroids—directly into the skin to reduce long-lasting nerve pain that follows shingles. If you've had persistent shingles pain for at least 3 months, this study may help ease your discomfort.
Hear when a new Postherpetic Neuralgia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.