Clin2
NCT07604025Possibly a fitNot yet recruiting

Medicine for chronic constipation and accidents in children

Encopresis With Constipation and Overflow Incontinence

Treatments studied

Part of Digestive system clinical trials.

This study tests two medicines, polyethylene glycol (a laxative) and senna, for children with long-term constipation and stool accidents. It aims to find which is better to reduce accidents and improve toilet habits.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
80 people
Ages
4 years to 17 years
Study type
Interventional

Who can take part

  • Children aged 4 to 18 years
  • Have chronic constipation with stool accidents (soiling) at least 4 times a week
  • Diagnosis of functional constipation (constipation not caused by another disease)
  • Have not previously been treated with laxatives like senna or polyethylene glycol

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07392203Not yet recruiting· Early Phase 1
Saline-glycerin enema for children with bowel leakage

This study tests whether a daily enema made with salt water and glycerin can help children who have bowel leakage (fecal incontinence) stay cleaner and more comfortable. It aims to improve daily life for children who have had certain bowel surgeries or conditions.

Sohag
NCT05821309Recruiting· Phase 4
Testing how a new enema routine changes gut bacteria

This study looks at how placing an antegrade (forward-flow) continence enema and starting a bowel flush routine may change your gut microbiome (your gut bacteria). It is meant for children who have long-lasting constipation that required a special surgical drainage channel.

Carmel, Indiana
NCT06825260Recruiting· Phase 4
PEG3350 vs Senna after urogynecologic surgery

This study compares two common laxatives to see which works better for preventing constipation after surgery for pelvic organ prolapse or stress urinary incontinence. It will help find the best way to keep you comfortable during recovery.

Syracuse, New York
NCT06543979Recruiting· Phase 1/Phase 2
Anorectal manometry for children with chronic constipation

This study is for children aged 4–16 who have long-term constipation that doesn't get better with standard laxatives. It uses a test called anorectal manometry to measure how well the muscles in the bottom work, which can help guide treatment.

Cairo
NCT07226739Recruiting· Phase 4
Toilet training program for children with delays

This study tests a program to help children with developmental delays overcome bowel and bladder accidents. It involves a structured toileting schedule and support for caregivers.

Atlanta, Georgia
NCT07723924Recruiting· Phase 2
Plecanatide for constipation in children and teens

This study tests a new medicine called plecanatide for children and teens with functional constipation. It aims to see if it helps improve bowel movements compared to a placebo (a pill with no medicine).

Birmingham, Alabama

Hear when a new Encopresis With Constipation and Overflow Incontinence trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.